Kludge Everywhere
Despite nearly 400 years of scientific revolution, Biology has been unable to deliver on crucial problems like effective cures for viral infections or cancer. Some of our best progress, like antibiotics, has been due to chance and random experimentation. You start a clinical trial for a hypertension drug and suddenly - whoah - all your subjects have hard-ons! Viagra is born. To be sure, chance plays a role in all endeavours, but Physics and Chemistry have a comprehensive theoretical basis powering systematic improvements, whereas Biology has been largely confined to kludges. Wanna treat cancer? Here, blast the patient with radiation and poison and hopefully the cancer will die first. They’re brilliant kludges, and I’m happy to have them, but it’s a far cry from the precision we’ve had elsewhere.
That’s from an excellent essay by Gustavo Duarte.